Change diapers immediately after urination or stool. Clean the skin with warm water or moist fragrance-free wipes. Dry the skin completely before putting on a new diaper, and apply a thin layer of protective ointment.
Use a zinc oxide cream to form a protective barrier with every diaper change to protect the skin and prevent irritation.
Let the baby spend some time daily without a diaper to allow the skin to breathe. Wash your hands after every diaper change to prevent spreading bacteria and fungi.